Foetal and neonatal outcomes in an era of active management of intrahepatic cholestasis of pregnancy
نویسندگان
چکیده
Background: Intrahepatic cholestasis of pregnancy is one kind hepatic disorder which unique to pregnancy. It associated with many adverse outcomes if not intervened at the right time. requires adequate clinical and biochemical correlation during management. Methods: A prospective observational study was conducted in a tertiary care hospital among 1397 patients who underwent delivery period from 01 July 2021 30 Jun 2022. Among population, those suspected be having IHCP were subjected laboratory tests confirmed cases further analysed for incidence form several maternal fetal factors by appropriate statistical test using IBM SPSS version 20.0 Results: During total out 174 showed signs suggestive IHCP. On subjecting these testing 53 diagnosed The 3.7% 28.30% (16/53) primigravida. There 22.64% (12/53) IVF pregnancies, 11.3% (6/53) twin pregnancies. Total (15/53) presented preterm labour. Of total, there 7.5% (4 /53) meconium-stained liquor. 54.71% (29/53) normal vaginal delivery, forceps VBAC 45.28% (24/53) LSCS this 70.8% (17/24) emergency caesarean 29.2% (7/24) elective deliveries, 75% (18/24) primary delivery. 25.4% (15/59) NICU admissions new born 28.8% (17/59) low birth weight babies. neonates seen have APGAR score less than 7 5 minute no stillbirth noted case Conclusions: causes significant neonatal morbidity major contributor liquor admission.
منابع مشابه
Management of intrahepatic cholestasis in pregnancy.
Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disease during pregnancy, characterized by otherwise unexplained pruritus in late second and third trimester of pregnancy and elevated bile acids and/or transaminases. ICP is associated with an increased risk of adverse perinatal outcomes for the fetus and the later development of hepatobiliary disease for the mother. Bile aci...
متن کاملIntrahepatic cholestasis of pregnancy.
Intrahepatic cholestasis of pregnancy is the most common pregnancy-specific liver disease that typically presents in the third trimester. The clinical features are maternal pruritus in the absence of a rash and deranged liver function tests, including raised serum bile acids. Intrahepatic cholestasis of pregnancy is associated with an increased risk of adverse perinatal outcomes, including spon...
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ژورنال
عنوان ژورنال: International journal of reproduction, contraception, obstetrics and gynecology
سال: 2023
ISSN: ['2320-1770', '2320-1789']
DOI: https://doi.org/10.18203/2320-1770.ijrcog20230123